模拟退火及紫外光谱法用于多组分维生素B含量分析

Application of simulated annealing and UV spectroscopy in multicomponent analysis of Vit.B

目的:研究能跨越局部最优而达全局最优的模拟退火算法,结合紫外可见及红外光谱法进行重叠峰分辨,用于多组分分析.方法:将模拟退火算法结合紫外光谱法用于复方药物V it.B四组分含量测定.结果:V it.B1,B2,B6和烟酰胺(NA)的回收率分别为100.1%,100.2%,99.9%和100.1%.结论:模拟退火算法结合紫外光谱法用于多组分复方药物的含量测定,操作简便,结果良好.

AIM： To work out simulated annealing algorithm which bypasses partial but reaches whole optimization and which is combined with ultra-violet （UV） and infrared radiation （IR） spectroscopy method to resolve overlapped peaks and to analyze multiple components. METHODS： Simulated annealing algorithm combined with UV spectroscopy was used to simultaneously determine the four contents in compound pharmaceuticals-VB. RESULTS： The recoveries of Vit. BI, 132, 136 and NA were 100.1%, 100.2%, 99.9% and 100.1% respectively. CONCLUSION： The simulated annealing algorithm combined with UV is suitable for the simultaneous determination of multi-components in compound pharmaceuticals.