多时段血糖控制对糖尿病肾病转归的影响研究

Analysis of 2-year follow up on diabetic nephropathy in patients under test and control of blood glucose more than 6 time in one day.

目的探讨多时段血糖控制对糖尿病肾病治疗的作用。方法对76例确诊2型糖尿病病人进行每月多时段血糖监测及根据结果进行降糖药物调整使血糖稳定,观察2年;对照组为35例根据空腹及早餐后血糖监测调整降糖药物。定期检查所有病人尿蛋白、血糖、血压及HbA1c等。结果两组糖尿病肾病发生或发展情况经过秩和检验P值小于0.05,两组间的处理结果的差别有统计学意义,说明多时段血糖控制组其肾病改善及稳定的阳性率高于对照组,而发生肾病加重的阳性率低于对照组。结论:多时段血糖控制可延缓2型糖尿病肾病的发生并对肾病有改善作用。

objective To study the onset and development of diabetic nephropathy undergoing 2 years. When treated with more than 6 points of blood glucose test and control in one day.Method Diagnosised 76 instances with type 2 diabetes（as experimental group） were treated with more than 6 points of blood glucose test and control in one day monthly,but diagnosised 35 cases as control group treated with 2 points of blood glucose test and control in one day morning monthly. All patients were observed for 2 years,and regularly examined urineary protein,blood glucose, blood pressure and HbA1c. Result The numbers of onset and development of diabetic nephropathy in experimental group were higher than those in control group. Conclusion The more than 6 points blood glucose test and control will delay the onset and development of complication as diabetic nephropathy in type 2 diabetes.