单宁酸对布氏田鼠能量代谢的影响

Effects of Tannic Acid Food on Energy Metabolism in Brandt's Voles (Lasiopodomys brandtii)

为了解单宁酸对成年布氏田鼠(Lasiopodomysbandtii**)能量代谢和产热的影响,本文采用含0、3·3%和6·6%单宁酸浓度的食物饲喂布氏田鼠21d,对其体重、基础代谢率、非颤抖性产热和能量收支等进行了测定。代谢率采用封闭式流体压力呼吸计测定;非颤抖性产热用皮下注射去甲肾上腺素诱导;能量摄入采用食物平衡法测定。结果发现:(1)单宁酸食物对布氏田鼠的体重没有明显影响;(2)取食含6·6%单宁酸食物的动物的基础代谢率于第10d高于对照组。20d时,3组动物的基础代谢率没有显著差异;(3)单宁酸食物对非颤抖性产热没有显著影响;(4)食用含单宁酸食物的动物的摄入能和消化能于第10d显著低于对照组,但第20d时则差异不显著。这些结果表明:布氏田鼠的基础代谢率和能量摄入对单宁酸的反应具有时段性,短期内能量消耗增加,随着动物对食物的适应,生理功能恢复到正常水平。

Plant secondary metabolites affect the survival, reproduction, and distribution of herbivores. In order to test the effects of plant secondary metabolite on energy metabolism and thermogenesis, we examined the changes in basal metabolic rate （BMR）, energy intake and nonshivering thermogenesis in captive Brandt＇ s voles （ Lasiopodomys bandtii, formerly Microtus brandti ） fed diets containing 0, 3.3% and 6.6% tannic acid respectively. Metabolic trials were performed by using the closed-circnit respirometer, and nonshivering thermogenesis was induced by subcutaneous injection of norepinephrine. The energy intakes were estimated with food trials. Voles fed the diets with 6.6% tannic acid increased basal metabolic rate compared with control at 10 days, and reduced the gross energy intake and digestible energy intake. After 20 days, voles fed diets containing tannic acid showed no sig- nificant changes in basal metabolic rate, gross energy intake and digestible energy intake. The apparent digestibility was kept sta- ble during the experiment. These results indicated that tannic acid can increase basal metabolic rate and energy intake within a short period and the changed physiological function returned to baseline for a long period. Tannic acid has no effect on body mass and no significant difference was detected in nonshivering thermogenesis between pre-and the end of experiment in Brandt＇ s voles. Brandt＇ s voles can adjust their physiological functions to match the changes in food conditions.