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Analysis of a Free Boundary Problem Modeling Tumor Growth 被引量:10

Analysis of a Free Boundary Problem Modeling Tumor Growth
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摘要 在这篇论文,我们学习从当模特儿肿瘤生长产生的一个免费边界问题。这个问题包括二未知功能:R = R (t) ,肿瘤的半径,和 u= u (r, t ) ,在肿瘤的营养素的集中。功能 u 在这个区域满足一个非线性的反应散开方程 0 < r < R (t) , t > 0,并且功能 R 满足包含 u 的一个 nonlinearintegro 微分的方程。在一些一般条件下面,我们作为 t →∞向静止答案建立短暂答案,一个静止答案的唯一的存在,和短暂答案的集中的全球存在。 In this paper, we study a free boundary problem arising from the modeling of tumor growth. The problem comprises two unknown functions: R = R(t), the radius of the tumor, and u = u(r, t), the concentration of nutrient in the tumor. The function u satisfies a nonlinear reaction diffusion equation in the region 0 〈 r 〈 R(t), t 〉 0, and the function R satisfies a nonlinear integrodifferential equation containing u. Under some general conditions, we establish global existence of transient solutions, unique existence of a stationary solution, and convergence of transient solutions toward the stationary solution as t →∞.
出处 《Acta Mathematica Sinica,English Series》 SCIE CSCD 2005年第5期1071-1082,共12页 数学学报(英文版)
基金 Project supported by the China National Natural Science Foundation,Grant number:10171112
关键词 自由边界问题 广义解 渐进线 瘤生长模型 非线性扩散方程 Free boundary problem, Tumor growth, Global solution, Asymptotic behavior
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