阴茎海绵体内注射治疗阳痿血管活性剂的选择

SELECTION OF VASOACTIVE DRUGS FOR ICI THERAPY OF IMPOTENT PATIENTS

自１９８６年６月至１９９４年１０月，采用罂粟碱／酚妥拉明（Ｐ／Ｒ）和前列腺素Ｅ＿１（ＰＧＥ＿１）经阴茎海绵体内注射（ＩＣＩ）治疗功能性阳痿者分别为１９５０例和２５０例。比较Ｐ／Ｒ和ＰＧＥ＿１应用结果：治疗成功率分别为９０％和８４％；持续勃起率分别为２．１８％和０％；注射疼痛率分别为０．６２％和１８．４％；局部硬结率分别为２．２３％和０％；剂量递增率分别为３３％和２０％。有关两者应用的选择方案给予讨论。

rom June l986 to October l994,papaverine/phentolamine(P/R)were administered byintracavernous injection(ICI)to 1950 functionally impotent patients and prostaglandin E1(PGE1)to 250cases,Different results of the P/R and PGEl were obtained,the therapy suc-cess rate was 90%and 84%respectively.The priapism rate was 2.18%and 0%reapective-ly.The pain rate caused by PG1 and P/R was 0. 62%and l8.4%respectively,The local in-duration rate was 2.23%and 0%respactively.The dose gradient indrease rate was 33%and20%respactively,A selection criteria of the P/R or PGE,was discussed.