莫沙必利联合开塞露应用于非消化道腹部手术后胃肠功能恢复的效果观察与护理

Observation of the effect of application of Mosapride combined with glycerin suppository on gastrointestinal function after nongastrointestinal abdominal surgery.

目的观察分析莫沙必利联合开塞露应用于腹部非消化道手术后胃肠功能恢复的效果。方法200例患者随机分为四组,A组于术后12h给开塞露40ml肛注;B组于术后6h给莫沙必利5mg口服;C组于术后6h给吗丁啉10mg口服,术后12h给开塞露40ml肛注;D组于术后6h给莫沙必利5mg口服,术后12h给开塞露40ml肛注。结果D组患者恶心、呕吐、腹胀发生率低,肛门排气恢复时间缩短,术后体重变化小,住院日减少,与各组间比较差异有显著性(P<0.05或P<0.01)。结论莫沙必利联合开塞露应用于腹部非消化道手术后可促进胃肠功能早期恢复,是一种安全、有效、经济的辅助用药方法。

Objective： To discuss the effect of application of Mosapride combined with glycerin suppository on gastrointestinal function after nongastrointestinal abdominal surgery. Methods： 200 cases were divided into four groups at random. Group A was given 40ml glycerin suppository through rectum 12 hours later postoperatively; Group B 5mg Mosapride orally 6 hours later ; Group C 10mg Dompride 6 hours later and 40ml glycerin suppository through rectum 12 hours later; Group D was given 5mg Mosapride orally 6 hours later 40ml glycerin suppository through rectum 12 hours later postoperatively. Re- suits ： The incidence of PONV was less, the hospitalization days was reduced, the time of recovering flatus shortened obvi- ously and the weight changed slightly. Conclusion： Application of Mosapride combined with glycerin suppository can promote the restoration of gastrointestinal function after nongastrointestinal abdominal surgery. The medication is safe, effective and economic.