复方丹参H_(303)对鼠类密闭性缺氧存活率及脑梗塞范围的影响

Effects iof Salvia Miltiorrhiga Preparation(Danshen H_(303))on Asphyxic Anoxia and Brain Infarction in Mouse

运用密闭性缺氧和阻断大脑中动脉引起脑组织急性缺血的动物模型,观察了口服3天或半个月后的复方丹参(H_(303))对其的作用。结果表现;H_(303)能提高小鼠的抗缺氧能力,延长动物的存活时间,并能改善大鼠因脑梗塞引起的组织坏死、水肿及炎症程度,使得脑组织逐步得以修复和再生。

In this paper the effects of salvia miltiorrhiga preparation(Danshen H_(303) at the third days and the fifteen days(P.O.)were studied by means of using models of asphyxic anoxia and abstruction arteria (?)medi(?) to couse brain tissue a(?)te ischemic.The results showed:H_(303) was able to enhance the resistance of organism to anoxia and prolong the survival time of anmial significanty.H_(303) also was able to improve degree of tissue necrosis,edema and inflamation during brain infarction.