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NF-κB在肝细胞及肝脏疾病中作用的研究进展 被引量:5

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摘要 核因子-κB(NF-κB)是近年来研究极为广泛的转录调控因子,具有多种转录调节活性。参与细胞因子、活化因子、生长因子和粘附分子及某些急性期反应蛋白转录活性的调控,在正常及疾病状态下、在肿瘤的发生和发展过程中有重要作用。NF-κB在肝细胞、肝癌细胞都有表达,在肝移植、肝缺血再灌注损伤等病理生理过程中均发挥重要作用。
作者 李理 刘长安
出处 《国外医学(临床生物化学与检验学分册)》 2005年第11期853-855,共3页 Foreign Medical Sciences(section of Clinical Biochemistry and Laboratory Medicine
基金 国家自然科学基金资助项目(30400424)
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