TACE、PVC、PEI三介入联合治疗晚期原发性肝癌的临床总结

Clinical Investigation of Combined Three Intervened Treatment of TACE.PVC.And PEI in Advanced Hepatic Cancer

目的:分析TACE、PVC、PEI三介入联合治疗晚期原发性肝癌的临床疗效。方法:将晚期原发性肝癌60例,分为两组进行治疗:经导管肝动脉栓塞化疗(TACE)组30例(对照组);TACE联合门静脉化疗及CT引导下无水酒精注射,即三介入联合治疗组30例(联合治疗组)。观察两组间的生存率及门脉癌栓的消失率。结果:对照组6、12、18、24个月生存率分别为56.7%(17/30)4、0%(12/30)、20%(6/30)、6.7%(2/30),门脉癌栓消失率43.75%(7/16)。而治疗组6、12、18、24个月生存率分别为76.7%(23/30)、56.7%(17/30)、36.7%(11/30)、16.7%(5/30),门脉癌栓消失率为64.7%(11/17)。两组间生存率及门脉癌栓消失率均有统计学意义(P<0.05)。结论:三介入联合治疗优于单纯栓塞化疗。

Objective： To explore the clinical efficacies of TACE. PVE. PEI for advanced hepatic cancer. Methods： Sixty cases of advanced hepatic cancer were divided into two groups. Thirty cases were treated with TACE （control group）and other 30 were with combined ATCE. PVC. and PEI （treatment group）. The two groups were compared for survival rate and disappearance rate of portal vein thrombosis, Resuls： the 6,12,18 and 24 mouths survival rate and disappearance rate of portal vein thrombosis of the control group were 56, 7 % （ 17/30）, 40 % （ 12/30）, 20 % （6/ 30）, 6.7 % （2/30）, and 43.75 % （7/16）, respectively; meanwhile those of the treatment group were 76.7%（23/30）,56.7%（17/30）,36.7%（11/30）,16.7%（5/30）, and 64.7%（11/17）. the outcomes were significantly different in the two groups in survival rate and disappearance rate of portal vein thrombosis （P〈0.05）. Conclusion： Three combined treatment is more effective than the simple TACE treatment.