短暂性脑缺血发作(TIA)定义的演变

Evolution of the definition of transient ischemic attack(TIA)

TIA的定义经历了20世纪50年代的1小时分界到1960—1970年确立的24小时分界。在无影像学帮助区分TIA与脑卒中的时代,这样的定义仅起临床分类作用,存在不可避免的缺陷。随着影像学技术的进步和溶栓治疗的发展,TIA已经成为发现和处理缺血性脑血管病的关键时机。新定义重新以1小时分界并强调没有组织学损害证据,有助于尽早发现和处理缺血性脑血管病。疾病定义的修订需要把医学科学发展与实践应用结合起来。

The definition of TIA began with one - hour cutoff in 1950s and established with 24 - hours cutoff during1960s and 1970s. During the period when no imaging techniques could help to differentiate TIA from ischemic stroke, such definition could only contribute to clinical classification, with inevitable shortcomings. With the development of imaging technique and thrombolysis therapy, TIA has become a good opportunity for identifying and managing ischemic cersbrovascular diseases. The New TIA definition employs the one - hour cutoff with emphasis on no brain lesion evidence. The new definition may help to identify and manage ischemic cerebrovascular diseases earlier. Revision of the definition of diseases calls for the combination of the development of medical science and clinical practice.