盐酸腹腔注射法在金黄地鼠肠粘连模型建立中的应用

Establishment of Intestinal Adhesion Model of Syrian Hamsters with Hydrochloric Acid Injection into the Abdominal Cavities

为探讨盐酸腹腔注射法制备金黄地鼠肠粘连模型的效果，将40只金黄地鼠分为5组进行对比观察。结果腹腔注射1％与0．5％盐酸后的两组均100％发生了肠粘连，腹腔注射0．25％盐酸组肠粘连的发生率为87％，0．5％盐酸腹腔注射法与Galili法相比肠粘连发生率无差异（X^2=0．25，P〉0．05）。结果显示，0．5％盐酸腹腔注射法在金黄地鼠肠粘连模型的建立中是一种经济、简便易行的方法。

The objective of the study is to establish the intestinal adhesion model of Syrian Hamsters with hydrochloric acid injection into their abdominal cavities. Fourty Syrain Hamsters were divided into 5 groups ,and hydrochloric acid of different concentrations was injected into the abdominal cavities of each group. Results showed that intestinal adhesion occurred 100 per cent in the groups of Syrain Hamsters underwent 1% and 0. 5% hydrochloric acid injections, that the intestinal adhesion occurrence rate was 87% in the group received 0. 25% hydrochloric acid injection, and that there was no statistical difference in the intestinal adhesion occurrence rate between the group underwent 0. 5% hydrochloric acid injection and Galili group （X^2 =0.25, P d0. 05）. It is suggested that 0.5% hydrochloric acid injection into the abdominal cavity of Syrian Hamster is a economic ＆ simple method in the establishment of intestinal adhesion model.