莲子对黄曲霉毒素（B_1）诱发的人体淋巴细胞姐妹染色单体互换和细胞周期状态的影响

The Effect of Lotus Seed on Aflatoxin B_1 induced SCE and CGC in Cultured Human Peripheral Lymphocyte

莲子对黄曲霉毒素（Ｂ_１）诱发的人体淋巴细胞姐妹染色单体互换和细胞周期状态的影响干侣仙，廖绵初，黄少珍（厦门大学抗癌研究中心，广西壮族自治区肿瘤研究所）肿瘤细胞遗传学和肿瘤形成过程的研究已表明［１］在细胞恶性转化和肿瘤形成的多阶段过程中，存在着突变，...

The effect on sister chromatid exchange(SCE) and cell generation circle(CGC) of human peripheral lymphocytes induced by AFB1 was detected using extracts of Lotus seed cotyledon and lotus plumule. It was discovered that the frequencies of SCE of ethanol extracts of lotus seed cotyledon were lower and the frequencies of SCE of physiological saline extracts of lotus plumule were higher than ethanol extracts. the level of M3 of CGC and the proliferation rate index(PRI) of lotus seed cotyledon ethanol extracts were near to those of the normal control,and the level of those lotus plumule extracts of ethanol and physiological saline were dropped significantly. The results show that lotus seed cotyledon has the capacity of decrease damage of chromatid by AFB1 and increase the rate of cell generation cycle.