腹腔化疗在胃癌根治术后的应用观察

Application of Celiac Chemotherapy after Radical Gastrectomy (70 cases reports)

目的探讨腹腔化疗在胃癌根治术后的应用观察。方法对1998年10月～2001年10月,胃癌获得根治切除术的患者70例,在术后早期应用5-氟脲嘧啶(5-Fu)进行腹腔化疗351例次。结果无一例发生腹腔出血、脏器穿孔、肠梗阻、腹腔化脓性感染、吻合口瘘、十二指肠残端瘘等并发症,腹腔化疗对全身尤其骨髓毒性作用小,随访3年以上,3年生存率为75.7%。结论腹腔化疗应成为胃癌根治术后辅助化疗的首选给药途径,提示加强腹腔化疗的观察护理,帮助患者顺利完成化疗,减少各种并发症的发生,提高生存质量。

Objective To discuss the application of celiac chemotherapy after radical gastrectomy. Methods 70 cases（351times） of gastric cancer were applied to celiac chemotherapy by 5-Fu early stages after operation. Resuits There was no complication such as internal hemorrhage, viscera perforation, intestinal obstruction, supparative infection. Anastomotic fistula and duodenal nub fistula etc, and less general toxicity, esp the bone marrow inhibition. All patients were followed up more than 3 years. The survival rate is 75.7%. Condusions celiac chemotherapy is the first-selected treatment for the sufferers after radical gastrectomy, and strengthening the nursing of celiac tubes will help them finish chemotherapy smoothly, reduce complications, improve their survival quality.