垂体后叶素在心肺复苏中的应用研究

Study on administration of vasopressin during cardiopulmonary resuscitation

目的研究垂体后叶素在心肺复苏中的作用。方法68例心跳停搏患者随机分为两组,肾上腺素标准剂量组(对照组)31例,肾上腺素联合垂体后叶素(治疗组)37例,各组分别观察自主循环恢复率及恢复时间。结果对照组、治疗组自主循环恢复率分别为25.8%、37.8%,治疗组的自主循环恢复率明显高于对照组;同时,治疗组自主循环恢复时间较对照组明显缩短。结论心肺复苏期间,联合使用肾上腺素、垂体后叶素较单独应用标准剂量肾上腺素能显著提高自主循环恢复率,缩短自主循环恢复时间。

Objective To study the effect of administrating vasopressin on cardiopulmonary resuscitation. Methods 68 patients with cardiac arrest were divided into 2 groups in randomly, 31 cases in control group were solely given epinephrine, 37 cases in observation group were given epinephrine combined with vasopressin. The rate and time of spontaneous circulation restoration were respectively observed in each group. Results The rate of spontaneous circulation restoration were 25.8% and 37.8% in the control group and observation group respectively, The rate of spontaneous circulation restoration in the observation group was significant higher than that in control group, the time of spontaneous circulation restoration in the observation group was significant shorter than that in control group at the same time. Conclusions Compared with the sole administration of epinephrine, the dministration of vasopressin combined with epinephrine may significantly increase the rate of spontaneous circulation restoration, shorten the average time of spontaneous circulation restoration during cardiopulmonary resuscitation.