降钙素原检测在鉴别细菌和病毒性肠道感染性疾病中的应用

Procalcitonin detection for the differentiation of gastroenteric infection by bacteria or human rotavirus

目的探讨降钙素原(PCT)对儿童感染性腹泻的诊断价值。方法采用半定量的胶体金免疫渗滤法对52例感染性腹泻患儿和20名正常儿童进行PCT检测。结果细菌性痢疾患儿组的PCT阳性率为41.2%(14/34),轮状病毒性肠炎组为5.6%(1/18),细菌性痢疾组与轮状病毒性肠炎组比较差异有显著性(P<0.01)。结论PCT水平与细菌感染相平行,是一项鉴别细菌和病毒性肠道感染性疾病的敏感指标。

Objective To investigate the diagnostic value of serum procalcitonin （PCT） level of children with infectious diarrhea. Methods The PCT level of 52 children with the infectious diarrhea and 20 healthy children was measured by a semi-quantitative colloidal gold immunofiltration assay. Results In the sera of children with bacillous dysentery and human rotaviral gastroenteritis, the positive rate of PCT was 41.2% （14/34） and 5.6% （1/18） respectively; The difference was significant （P 〈0.01 ）. Conclusions The increasing PCT could be related to bacilly infections. Serum PCT level may be a sensitive marker to identify the gastroenteric infection by bacteria or human rotavirus.