期刊文献+

江苏无锡地区社区及医院败血症病原菌与预后的比较 被引量:2

下载PDF
导出
摘要 目的比较社区及医院败血症的病原菌分布特点、预后及相关因素.方法收集无锡地区2000~2003年4家综合性医院血培养阳性病例共480例,统计分析不同感染类型、相应的病原菌构成及其预后的差别.结果480例血培养阳性患者77.3%为社区获得性菌血症(CABSI),22.6%为医院获得性菌血症(HABSI).CABSI的主要病原菌是凝固酶阴性葡萄球菌(38.0%)、大肠埃希菌(17.8%)、沙门菌(9.4%)和金黄色葡萄球菌(8.3%);而HABSI常见病原菌依次为凝固酶阴性葡萄球菌(17.4%)、念珠菌(14.7%)、大肠埃希菌(12.8%)、铜绿假单胞菌(11.9%)和克雷伯杆菌(10.1%).HABSI的平均年龄52.2岁显著高于CABSI患者28.1岁(P<0.001).HABSI患者的病死率20.2%显著高于CABSI患者3.0%(P<0.001);医院感染组中,铜绿假单胞菌所致的感染病死率最高达38.5%,而社区感染组中肺炎链球菌所致的感染病死率最高,为16.7%.结论社区及医院败血症的病原菌构成、科室分布、病死率均不同,临床应有针对性地进行抗感染治疗,以降低菌血症的病死率.
出处 《临床检验杂志》 CAS CSCD 北大核心 2005年第6期466-467,共2页 Chinese Journal of Clinical Laboratory Science
  • 相关文献

参考文献2

  • 1Esel D,Doganay M,Alp E,et al.Prospective evaluation of blood cultures in a Turkish university hospital:epidemiology,microbiology and patient outcome[J].Clin Microbiol Infect,2003,9(10) :1038-44.
  • 2Javaloyas M,Garcia-Somoza D,Gudiol F.Epidemiology and prognosis of bacteremia:a 10-y study in a community hospital[J].Scand J Infect Dis ,2002,34(6):436-441.

同被引文献26

  • 1黄仁刚,江南.败血症98例临床分析[J].现代医药卫生,2007,23(9):1271-1273. 被引量:2
  • 2Dombrovskiy VY, Martin AA, Sunderram J, et al. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States : a trend analysis from 1993 to 2003 [ J ]. Crit Care Med,2007, 35(5) :1244-1250.
  • 3Protti A, Singer M. Bench-to-bedside review: potential strategies to protect or reverse mitochondrial dysfunction in sepsis-induced organ failure[J]. Crit Care,2006,10(5) : 228.
  • 4Vaschetto R, Protti A. Biomarkers of sepsis in long-term critically ill patients[J]. Minerva Anestesiol,2010,76(10) : 771-772.
  • 5McGrane S, Girard TD, Thompson JL, et al. Procalcitonin and C-re- active protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients [ J]. Crit Care,2011,15 (2) : R78.
  • 6Oliveira CF, Botoni FA, Oliveira CR, et al. Proealeitonin versus C- reactive protein for guiding antibiotic therapy in sepsis: a randomized trial[J]. Crit Care Med,2013, 41 (10) :2336-2343 .
  • 7Koeze J, Hendrix MG, van den Bergh FA, et al. In critically ill pa- tients the proealeitonin level can be misleading[ J]. Crit Care,2011, 15(2) : 422.
  • 8Wolff M, Bouadma L. What procaleitonin brings to management of sepsis in the ICU[J]. Crit Care,2010,14(6) : 1007.
  • 9Shozushima T, Takahashi G, Matsumoto N, et al. Usefulness of pre- sepsin(sCD14-ST) measurements as a marker for the diagnosis and severity of sepsis that satisfied diagnostic criteria of systemic inflam- matory response syndrome [ J ]. J Infect Chemother, 2011,17 ( 6 ) :764-769.
  • 10Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/AC- CP/ATS/SIS international sepsis definitions eonferenee [ J ]. Crit Card Med,2003,31 (4) :1250-1256.

引证文献2

二级引证文献21

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部