支气管肺泡灌洗液细胞学检查及CEA_（McAb）测定对周围型肺癌的诊断意义

The Clinical Significance of Cytological Examination and CEA_(McAb) Assay of BALF in Diagnosis of Peripheral Lung Cancer

对５６例周围型肺癌患者行支气管肺泡灌洗术，其中３１例患者选用ＰＴ灌洗液，２５例患者选用生理盐水。结果：在ＰＴ灌洗液组，支气管肺泡灌洗液（Ｂｒｏｎｃｈｏａｌｖｅｏｌａｒｌａｖａｇｅｆｌｕｉｄ，ＢＡＬＦ）细胞学检查阳性率为６４．５％，高于生理盐水组（２８．０％）（Ｐ＜０．０５）。而二者ＢＡＬＦＣＥＡ＿（ＭｃＡｂ）阳性率各为６７．７％、５０．２％，差别不显著（Ｐ＞０．０５）。在ＰＴ灌洗液组，有１例隐匿型肺癌确定了病变部位。表明，对于周围型肺癌的ＢＡＬＦ细胞学检查及ＣＥＡ＿（ＭｃＡｂ）测定，采用ＰＴ灌洗液优于生理盐水，可明显提高诊断率，并可帮助确定隐匿型肺癌的部位。

ronchoalveolar lavage(BAL)was performed in 5 6 patients with peripheral lung cancer. PTlavage fluid was used in 31 cases and physiological saline in 25 ones of the 56 patients.The positive rateof cytological examination of bronchoalveolar lavage fluid(BALF)was 64.5%in the group of PTlavage fluid,higher than that of the group of physiological saline(28.1%)and the difference was significant( P<0.05).While thepositive rate of CEAMcAb assay in both groups were 6 7.7%and 5 0.2%respectively,and the difference was not significant(P >0.05).Moreover,in the group of PT lavagefluid,the location of latent lung cancer was determined in one patient.All above indicate that PT lavagefluid is superior to physiological saline in the cytological examination and CEAMcAb assay of BALF. PTlavage fluid can increase the rate of the diagnosis of peripheral lung cancer,and determine the positionof latent lung cancer.