精神分裂症的探索性眼球活动研究

Study on the Exploratory Eyeball Movement of Schizophrenia Patients

目的研究精神分裂症患者的眼球活动特点。方法采用病例对照研究设计测查80例精神分裂症患者和58例疑似精神分裂症患者及51例正常对照的探索性眼球活动,记录凝视点(NEF)和反映性探索评分(RSS)。结果精神分裂症组、疑似精神分裂症患者组与正常对照组NEF及RSS的比较,差异均有显著性(P<0.01)。精神分裂症组、疑似精神分裂症组NEF及RSS的比较,差异均无显著性(P>0.05)。RSS<7是区分精神分裂症和非精神分裂症的较特异性的分界值(kappa=0.801,kappa>0.75)。结论RSS可以作为精神分裂症的特异性生物学指标和辅助诊断指标。

[ Objective] To study the eyeball movement of schizophrenia patients. [ Methods ] The eyeball movements of 80 cases of schizophrenia patients, 58 cases of suspected schizophrenia patients and 51 normal people were detected; the NEF and RSS were recorded. [Results] Significant difference was found between the schizophrenia group, suspected group and the control group （P 〈 0.01）; no significant difference was found between the schizophrenia group and the suspected group （ P 〉 0. 05 ） ; RSS 〉 7 could be considered as the special dividing numerical value to distinguish schizophrenia and non schizophrenia （ kappa = 0. 801, kappa 〉0. 75 ）. [ Conclusion] RSS could be used as a special biological index and auxiliary index for diagnosis.