蒂洛安与催产素促宫颈成熟临床对比观察

A Comparison Study of Prasterone Sulfate (DHA-S) and Oxytocin in Cervical Ripeness

对105例孕周≥37周、宫颈Bishop评分≤5分的孕妇行计划分娩。72例应用蒂洛安促官颈成熟,33例应用催产素作为对照。结果:蒂洛安促成熟总有效率达90％,催产素为64％。引产成功率蒂洛安组为81.48％,催产素组45.00％,两组有显著性差别(P<0.005)。两组用药对母婴均无不良反应。研究结果表明:蒂洛安注射液能明显提高宫颈成熟率及引产成功率,且安全简便有实用价值。

Of 105 women with gestation≥37 weeks who were needing programmed deliveries but whose Bishop scoring≤5,72 cases were treated with DHA-S and 33 cases respectively with oxytocin. Results: 90% of patients in DHA-S group and 64% in oxytocin group obtained cervical ripeness respectively. The rates of successful induced labor after dosing were 81- 48% with DHA-S and 45. 0% with oxytocin. There were signifi-ciant differences between the two groups (P<0. 005). There were no side effects after dosing within the two groups. The results of analysis showed DHA-S could apparently increase cervical ripeness and proved to be an easy to handle,safe and economical method.