藤茶辅助降血脂作用的研究

Study on Ampelsis grossedentata to Lower Plasma Lipids Level

目的:本文主要研究大别山产藤茶的辅助降血脂作用,为开发防治高血脂的保健食品提供科学依据。研究方法:即用高脂饲料喂养动物形成脂代谢紊乱,再给予动物藤茶提取物经口灌胃30d,随机选择100名志愿受试者,每天按9g泡饮45d后,检测动物和人血清中TC、TG、HDL-C三项指标,动物试验结果表明:高剂量组总胆固醇含量下降明显,中、高剂量组总胆固醇含量下降幅度分别为16.7%、23.1%。低、中、高剂量组甘油三酯含量下降明显,低、中、高剂量组甘油三酯含量下降幅度分别为17.4%、17.8%、19.1%。低、中、高剂量组高密度脂蛋白胆固醇含量升高明显,低、中、高剂量组平均升高值为4.64、5.03、4.26mg/dl。人体试食试验结果表明:试验组降总胆固醇有效率为42%、降甘油三脂有效率为72%、降血脂有效率为28%,受试者血清总胆固醇、甘油三脂明显降低。结论:藤茶具有辅助降血脂作用。

Objective： To study the effect ofAmpelsis grossedentata on lowering plasma lipids level. Methods： The hyperlipemia rats were fed with Ampelsis grossedentata on three different dosages respectively everyday. After 30d, the levels of TC,TG and HDL-C were assayed.100 patients with primary hyperlipidemia were randomly allocated into two groups, one treated group and the other control group. Patients in the treated group were given 9g/d ofAmpelsis grossedentata. After 45d, the level of TC,TG and HDL-C were assayed. Results： the TC and TG level of rats could be lowered, the HDL-C level of rats could be increased. Whereas the effective rate of the patients treated group on reducing levels of TC, TG and plasma lipids were respectively 42%, 72% and 28%.Conclusion： In the study, Ampelsis grossedentata could lower the plasma lipids level.