血清CRP在小儿急性感染性疾病中临床意义的探讨

The Discussion for the Clinical Significance of Serologic CRP in Acute Infective Diseases in Children Pediatric department

目的探讨小儿急性感染性疾病中血清C-反应蛋白(CRP)水平变化及疗效判断。方法检测600例急性感染性疾病的小儿和300例健康儿的血清CRP及白细胞(WBC)总数、分类计数。结果(1)急性细菌性感染患儿的血清CRP水平显著高于对照组患儿,P<0.01;(2)急性细菌性感染组与病毒组、对照组相比血清CRP水平有显著差异性,p<0.01。结论急性细菌性感染组患儿血清CRP水平显著升高,特别是显著高于病毒感染组。在小儿急性感染性疾病时检测血清CRP水平可以早期、正确、灵敏地鉴别引起感染的致病因素,有助于临床做出及时治疗及合理使用抗生素。

objective To investigate the serologic C-reaction protein（CRP） level in the acute infective diseases and evaluation of therapeutic effect. Method The serologic CRP and White blood cells（WBC）account and sorted groups in 600 case children suffered from acute infective diseases and 300 healthy children have been tested for the investigation. Results （1） the general CPR level in acute bacterial infection of patients was significantly higher than that in the control CPR level in acute bacterial infection of patients was significantly higher than that in the control group P〈0. 01. （2）The bacterial infective group compared with the viral and control group, serum CPR levels were quite different and remarkable P〈0. 01. Conclusion The CRP level in the bacterial group was obviously higher than that in viral group. For the children suffering from acute infective diseases, the results of serologic CRP level in patients may distinguish different clinical pathogens early, accurately and sensitively. It is very helpful to make a timely treatment and the guide for the antibiotic selection effectively.