低分子肝素两种不同注射方法对皮下出血的影响

Influence of subcutaneous haemorrhage between two different methods about giving low-molecular-weight haparin(LMWH)

目的:探讨低分子肝素两种不同皮下注射方法与皮下出血发生率的关系,寻找最佳注射方法。方法:选择冠状动脉支架植入术后应用低分子肝素治疗的患者31例,随机分为两组,实验组18例,对照组13例。实验组采用注射前按摩局部皮肤,注射后按压的方法,对照组采用常规注射后按压方法。每例患者注射14次,共注射434例次。观察两组患者皮下出血发生情况。结果:实验组皮下出血发生率显著低于对照组(P<0.01)。结论:注射前按摩局部皮肤可促进药物吸收,降低皮下出血发生率。

objective： Discussing the relation of pre- injection and the morbility of subcutaneous haemorrhage of LMWH, find out an efficient method of injection. Methods：Select 31 patients who Were given LMWH after having coronary inserted with a stent . they were randomly divided into test group（n= 18） and control group（n= 13） ,The test group using massaging local skin pre- injection and press method of after injection,the control group only using press method of after injection, and to be observed the cases of subcutaneous haemorrhage . Results： The rnorbility of subcutaneous haemorrhage of the test group was lower than the control - group（P 〈 0.01）. Conclusion： Massaging the local skin pre- injection can accelerate drug absorbing, and lessen the morbility of subcutaneous haemorrhage.