阿昔洛韦治疗小儿咽-结合膜热的疗效观察

Observation of the curative effect of acyclovir on pharyngo-conjunctival fever

目的:探讨阿昔洛韦治疗小儿咽-结合膜热疗效。方法:将80例咽-结合膜热患儿随机分为阿昔洛韦组和利巴韦林组,分别给予阿昔洛韦、利巴韦林治疗。两组均计数发热天数及眼结合膜炎持续时间,同时观察药物的不良反应。结果:阿昔洛韦组平均发热天数明显短于利巴韦林组(P<0.01)。眼结合膜炎持续时间,阿昔洛韦组明显短于利巴韦林组(P<0.01)。两组药物治疗过程中仅少数病人出现轻度恶心、呕吐等不良反应,停药后症状缓解。结论:阿昔洛韦治疗咽-结合膜热较利巴韦林更有效。

Objective： To investigate the curative effect of aciclovir on pharyngo-conjunctival fever. Methods： 80 children with pharyn-go-conjunctival fever were divided into two groups, aciclovir treatment group and virazole treatment group. The two groups were treated with acyclovir and virazole respectively. The durations of fever and of conjunctivitis of both groups were compared, and meanwhile the side effects of two drugs were observed. Results： The duration of fever in aeyelovir group was significantly shorter than that of virazole group, （P 〈 0.01 ）;the duration of conjunctivitis in aciclovir group was also shorter than that of the virazole group （P 〈 0.01 ）. No serious side-effect of two drugs was found. Coneluslons： Aeielovir is more effective than virazole on pharyngo-conjunetival fever.