摘要
目的：术前判定患者对肝素的敏感程度，决定能否施行体外循环下的心内直视手术。方法：体外肝素抗凝度检测。结果：本法与活化凝血时间（ＡＣＴ）法比较，具有较高的精密度及特异性。体外肝素化，肝素钙１～１５ｍｇ／ｋｇ体重范围内，具有良好线性关系，与ＡＣＴ法检测结果比较显著相关（ｒ＝０．９９６７）。结论：本法可用以预测患者对肝素的敏感程度。
Objective: TO evaluate the sensitivity of patients to heparin preoperatively so as to assess the feasibility of open heart surgery under extracorporeal circulation. Metheds: In vitro heparin calcium anticoagulability assay was used to study patients (n=128) of open heart surgery.Results: The precision and specificity of in vitro heparin calcium anticoagulability assay was better than conventional ACT assay. Within 1-15mg/kg heparin calcium, in vitro heparinization had a good linearity and correlated positively with ACT assay (r=0.9967).Conclusion: In vitro heparin calcium anticoagulability assay preoperatively could be used to predict the sensitivity of patients to heparin.
出处
《中国循环杂志》
CSCD
1996年第4期229-231,共3页
Chinese Circulation Journal
关键词
肝素
抗凝度
体外循环
心内直视手术
In vitro heparin anticoagulability
ACT assay
Open heart surgery
Extracorporeal circulation
