摘要
目的:本文介绍应用液氮保存的、取材于新生儿带瓣大动脉,作为婴幼儿复杂先天性心脏病矫治术中应用的经验。方法:1993年10月至1994年12月间27例患儿在体外循环下行重症法乐四联症或右室双出口根治术。15例应用我院制备、具有活性的同种带瓣大动脉跨环加宽右室流出道。平均体重为9.50±2.04kg,另12例则用自体心包片为跨环加宽右室流出道材料,平均体重10.42±1.95kg。术后1周至9个月间用超声心动图评价肺动脉反流程度。结果:全组无死亡,术后9个月同种瓣组肺动脉瓣反流40.12±2.56%,自体心包组肺动脉瓣反流70.00±10.61%。结论:液氮保存的新生儿带瓣大动脉具有良好活性,作为跨肺动脉瓣环补片材料矫治复杂先天性心脏病时肺动脉反流明显低于自体心包片。
Objective: This study was conducted to describe the experience of using cryopreserved homografts of valved great arteries from neonates for the corrective operations of complex congenital heart diseases. Methods: From October 1993 to December 1994, 27 pediatric patients with severe tetralogy of Fallot or double-outlet of right ventricle underwent corrective operations with CPB. Viable homografts with valves of great arteries prepared in our laboratory were used to enlarge the RVOT with transannular patch in 15 patients (9.50±2.04 kg) and autogenous pericardial patches were used in the remaining 12 patients (10.42±1.95 kg). The degrees of regurgitation of the pulmonary valves 1 week and 9 months postoperatively were estimated by echocardiography. Results: All of the patients had recovered. Regurgitation of the pulmonary valves was 40.12±2.56% in the homograft group and 70.00±10.61% in the autogenous pericardial group. Conclusion: Cryopreserved homografts of valved great arteries from neonates have excellent viability and the postoperative regurgitation of the pulmonary valve was much lower in the homograft group than that in the autogenous pericardial patch group in corrective operation of complex congenital heart diseases to enlarge the RVOT with transannular patch.
出处
《中国循环杂志》
CSCD
1996年第3期148-151,共4页
Chinese Circulation Journal
关键词
婴幼儿
先天性心脏病
新生儿
主动脉
肺动脉
Homograft of valved great arteries from neonates
Complex congenital heart diseases
Operation