摘要
本实验在环磷酰胺免疫功能低下小鼠模型、观察了CPPQ对小鼠外周血白细胞总数,胸腺和脾脏重量,网状内皮系统吞噬能力及细胞免疫功能的影响。结果表明,CPPQ不仅能抗免疫功能低下小鼠外周血白细胞减少及胸腺和脾脏重量的减轻,并能增强正常和免疫功能低下小鼠网状内皮系统的吞噬功能。同时能促进免疫功能低下小鼠的淋巴细胞转化,而对白细胞介素Ⅱ活性无明显影响。
This paper investigated the effects of CPPQ on the WBC numbers,thymus and spleenweight, phagocytosis of reticuloendothelial system and cell-mediated inimunity of mice using the im-munosuppresive mice model induced with cyclophosphamide.It was found that CPPQ not only couldoppose leukopenia of surrounding blood but also could increase the weight of thymus and spleen in im-munosuppresive mice,and strengthen phagocytosis of reticuloendothelial system in normal and im-munosuppresive mice.At the same time,CPPQ could improve lymphocyte transformation and had noobvious effects on IL一2 activity in immunosuppresive mice.
出处
《白求恩医科大学学报》
CSCD
1996年第2期137-139,共3页
Journal of Norman Bethune University of Medical Science
关键词
西洋参根
粗多糖
环磷酰胺
免疫器官
细胞免疫
CPPQ
cyclophosphamide
immune organs
phagocytosis
cell-mediated immunity