恩施富硒藤茶安全性毒理学实验研究

Study on the Toxicology of Se-Enriching Ampelopsis Grossedentata from Enshi

根据保健食品检验与评价技术规范对恩施州富硒藤茶安全性进行了评价。急性毒性试验结果表明,受试藤茶属无毒级;3项致突变试验结果均为阴性。大鼠90天喂养试验中,藤茶各剂量组动物生长发育良好,对体重、食物利用率无不良影响。各剂量组血常规与对照组无显著差异。大鼠血清ALT、AST、BUN、TRI、CHO、CRE、GLU、ALB、TP测定结果与对照组比较无显著差异。脏器比值与对照差异不明显。肝、心、脾、肾、胃肠、睾丸、卵巢等器官外观和组织切片与对照比均未发现实质性病理改变。说明饮用恩施富硒藤茶安全无毒。

The water extract of Enshi Se-enriching Tengcha（ESTC） on the animal safety was investigated according to the Standard of Health Food Test and Assess. Acute toxicity test on mice showed that LD50 was greater than 30 g/kg.bw. Three genetic tests showed negative results. 90 days feeding test showed that the outer appearance, behavior, weights, organ coefficients, the indexes of hematology and biochemistry in rats have no significant difference comparing with the control group. Significant pathological changes of inherent organs were not discovered. All results showed that ESTC was safet for rats.