电刀牙龈成形术对高血糖及凝血功能障碍大鼠牙龈组织的影响

The influence of electronic gingivoplasty on the gingival tissue of rats with high blood sugar or with blood coagulating dysfunction

目的:通过动物实验探讨对高血糖及凝血功能障碍患者实施电刀牙龈成形术的可能性。方法:制作高血糖及凝血功能障碍SD大鼠模型并对它们进行电刀及手术刀牙龈成形术;对高血糖及对照组SD大鼠术后1、24、72h及1、2周的牙龈标本进行组织学观察;对凝血功能障碍及对照组的SD大鼠采用纸片法观察术中出血情况。结果:电刀牙龈成形术与手术刀牙龈成形术的牙龈组织学反应过程基本相似,高血糖组施行电刀牙龈成形术的大鼠较施行手术刀牙龈成形术的大鼠术后炎症反应稍轻,组织修复稍快;对凝血功能障碍及对照组SD大鼠,施行电刀牙龈成形术与施行手术刀牙龈成形术相比术中出血较少(统计学上有显著性差异)。结论:电刀牙龈成形术对高血糖及凝血功能障碍SD大鼠较手术刀牙龈成形术具有优势。

Objective：To study the feasibility of electronic： gingivoplasty on the subjects suffering from high blood sugar or blood coagulating dysfunction on rat model. Methods：Electronic gingivoplasty was performed in 10 SD rats with high blood sugar and 10 with blood coagulating dysfunction on the right side of mandible and scalpel gingivoplasty on the left. For each group of diseased rats 10 healthy rats were used as the controls. Gingival tissue slices of the rats with high blood sugar and the controls were obtained 1,24, 72 hours, one and two weeks after operation respectively, and processed for histological observation. The bleeding condition were evaluated with paper tips during the operations on the rats with blood coagulating dvsfunction and the controls. Results：The process of histological reaction in the tissues of operation area after electronic gingivuplasty was basically similar to that after scalpel gingivoplasty, Electronic surgery caused more slight inflammatary reaction than scalpel surgery in high blood sugar group. The amount of bleeding during electronic surgeU was significantly smaller than that during scalpel surgery in blood coagulating dysfunction group. Conclusion：Electronic surgery is feasible for gingivoplasty on the subjects with high blood sugar or blood coagulating dysfunction.