细菌性前列腺炎病原菌及临床耐药情况分析

Clinical drug resistanting analysis of chronic prostatitis

目的分析汕头地区慢性前列腺炎(CP)病原菌的分布及耐药情况,为确定病原菌分布情况和临床治疗提供参考依据。方法细菌鉴定及药敏试验采用V ITEK-60全自动细菌鉴定仪。结果葡萄球菌是汕头地区CP的主要致病菌(67%),其中表皮葡萄球菌的检出率最高,为21.58%。葡萄球菌引起的CP对苯唑西林、头孢唑林、氨苄西林-舒巴坦、阿莫西林-克拉维酸和红霉素等基本无效;而肠球菌对青霉素耐药率为0。治疗首选万古霉素、呋喃妥因、克林霉素和利福平等抗生素。结论该地区CP的致病菌以葡萄球菌为主,其中表皮葡萄球菌已成为CP的主要病原菌。为减少浪费、提高疗效,建议根据药敏结果选择抗生素。

Objective To investigate the etiology and susceptibilit of chronic prostatitis in Shantou area recently three years. Methods Bacteria identification and antibiotic susceptibility testing were performed by the VITEK auto-microbic system. Results The most common pathogens were Staphylococcus （67%） among them 21.58% were Staphylococcus epidermidis. Oxacillin, cefazolin, ampicillin/sulbactam, amoxicillin/clavulanic acid and erythromycin were almost ineffciency to the chronic prostatitis caused by staphylococcus. And the resistant rates of Enterococcus to penicillin was 0. The first choice of antibiotic in theraping chronic prostatitis was vancomycin,nitrofurantoin,clindamycin and rifampin. Conclusion The main pathogens were staphylococcus in Shantou areas, Staphylococcus epidermidis had been the most common pathogens of chronic prostatitis,using antibiotics in clinical therapy must based on the results of susceptibility of pathogens.