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吸收系数法测定吡嗪酰胺片中溶出度的研究 被引量:1

Determination of dissolution of pyrazinamide tablets by absorption coefficient method
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摘要 目的:建立吸收系数法测定吡嗪酰胺片中的溶出度。方法:采用紫外分光光度中的吸收系数法,吸收系数E_(1cm)^(1%)为652。结果:本法与对照品法无显著性差异。结论:本方法简便易行、快速、准确,可作为该制剂的质量控制方法。 Objective: To establish an absorption coefficient method for determination of the dissolution of Pyrazinamide tablets. Methods : The ultraviolet- spetrophotometry-absorptivity( 652 ) was used. The absorption coefficient( E1cm%1%) was 652, Results: There is no significent difference between absorption coefficient method and standard method, Conclusion: The method is simple, quick and accurate, It can be accepted for the quality control of pyrazinamide tablets.
机构地区 北京军区药检所
出处 《药学实践杂志》 CAS 2005年第6期369-370,共2页 Journal of Pharmaceutical Practice
关键词 吡嗪酰胺片 吸收系数法 溶出度测定 pyrazinamide tablets absorption coefficient determination of dissolution
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  • 1.中国药典2005年版·二部[S].,2005.附录:22.

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