客体与空间工作记忆的分离:来自皮层慢电位的证据

Dissociation of Object and Spatial Working Memory: Evidence from Slow Cortical Potentials

利用128导事件相关电位技术,采用延迟匹配任务的实验范式,测查了16名正常被试在完成客体任务和空间任务时的皮层慢电位(slow cortical potentials,简称sp成分),实验发现:在后部脑区,客体工作记忆与空间工作记忆在慢波活动的时间上存在分离,空间任务更早的诱发出负sp成分,并且空间任务激活更多的后部脑区;左下前额叶在客体工作记忆任务与空间工作记忆任务中都有激活,并且激活强度不存在显著差异;背侧前额叶主要负责客体信息的保持与复述,但左右背侧前额叶的激活强度存在不对称性。

This study used delayed matching task. Slow cortical potentials were measured when 16 normal participants were performing object and spatial working memory task. The results were as follows： at global posterior brain regions, dissociation in time of slow cortical potentials between object and spatial working memory task was found, and excessive posterior brain regions were activated in spatial working memory task. Left inferoprefrontal cortex（LIPFC） was activated in object and spatial working memory task, and there was not significant difference in intensity of activation. The dorsolateral prefrontal cortex（LDPFC） was responsible for maintenance and rehearsal of object information, but there was not symmetrical in intensity of activation between left and right dorsolateral prefrontal cortex.