中西医结合治疗胆汁反流性胃炎30例临床观察

Clinical Observation on the Treatment of 30 Patients with Bile Reflux Gastritis by Traditional Chinese Medicine Combined with Western Medicine

目的：观察胃肠舒联合铝碳酸镁治疗胆汁反流性胃炎的效果。方法：60例胆汁反流性胃炎患者随机分为胃肠舒和贝络纳组各30例,前组口服胃肠舒,每日1剂；后组口服贝络纳15mg／天；两组均同时服用铝碳酸镁1.0g次,3次／天,疗程为4周。两组于治疗前后进行临床症状、胃镜下胆汁反流程度分级和胃粘膜病理积分评价。结果：治疗后胃肠舒组和贝络纳组显效率、总有效率分别为43％、87％和33％、83％,胃镜下两组联合用药均可以明显改善患者的胃粘膜炎症,与治疗前比较差异有显著性(P＜0.05,P＜0.01),两组治疗胆汁反流性胃炎的疗效相近。结论：胃肠舒联合铝碳酸镁是治疗胆汁反流性胃炎的有效药物。

Objective：To observe the therapeutic effect of Wei-chang shu combined hydrotalcid on bile reflux gastritis. Methods：sixty patients with bile reflux gastritis were randomly divided into Wei-chang shu group（n=30） and Mosapride Citrate tablets group（n=30）. Patients in the Wei-chang shu group were treated with Wei-ehang shu ,one dose per day,and patients in the Mosapride Citrate tablets group were treated with Mosapride Citrate tablets, 15mg per day, and all patients were combined with hydrotalcid 3g per day for 4 weeks. Results：After therapy,the markedly effective rate was 43% and the effective rate was 87% in Wei-chang shu group,while 33% and 83% in the Mosapride Citrate tablets group. The levels of gastric mucosa injury in gastroscope were obviously improved after therapy compared with ones before therapy in both groups, respectively（P〈0.05 or P〈0.01 ）. It indicated that the therapeutic effect was close in the both group. Conclusion：Wei-chang shu combined hydrotalcid were useful in treating bile reflux gastritis.