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强直性肌营养不良的激发重复神经电刺激研究

Activation repetitive nerve stimulation studies on myotonic dystrophy.
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摘要 对9例强直性肌营养不良(MyD)患者行激发重复神经电刺激(ARNS)检查。1例(11%)ARNS前见序列复合肌肉动作电位(CMAPs)波幅递减,8例(89%)ARNS后出现首位CMAP波幅降低,其中6例(67%)伴序列CMAPs波幅递减。首位CMAP波幅降低出现率和平均降低程度随病程延长而加重。认为MyD患者的骨骼肌兴奋收缩反应减弱,可能与漫长病期致正常肌纤维数量减少及病变肌膜去极化过程减弱有关。 ARNS studies were made on 9 cases of MyD,8 cases (89%) showed decrease in amplitude of first compound muscle action potential (CMAP) which represented all CMAPs.And among them 6 cases showed declining response in amplitude of train CMAPs.The appearance rate of decrease in amplitude and the severity of mean decrement were related to the durations of the disease.We conjecture that the skeletal muscles of MyD have changes in excitability and contractility,and that these changes may be caused by the decreace in the number of normal muscle fibers.The declining response of MyD was different from myasthenia gravis.
出处 《临床神经病学杂志》 CAS 1996年第3期146-148,共3页 Journal of Clinical Neurology
关键词 强直性 肌营养不良 神经电刺激 递减反应 Myotonic dystrophy Activation repetitive nerve stimulation Declining response
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