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阿托伐他汀干预对急性冠脉综合征患者血浆CRP和BNP水平的影响

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摘要 目的探讨阿托伐他汀干预对急性冠脉综合征(ACS)患者血浆C-反应蛋白(CRP)和B型钠尿肽(BNP)水平的影响。方法采用随机开放法将ACS组分成常规组和阿托伐他汀组进行为期8周的干预,分别测定治疗前及治疗后4周和8周患者血浆CRP和BNP的浓度变化,比较治疗前后的血浆CRP及BNP水平变化。结果ACS患者治疗4周和8周后,阿托伐他汀组血浆CRP及BNP水平均明显下降,而常规组BNP水平明显下降,CRP无明显变化。结论ACS的发生与机体炎症反应激活有关。阿托伐他汀能够降低血浆CRP和BNP水平,在ACS的治疗中具有重要作用。
出处 《医学信息(西安上半月)》 2005年第12期1711-1712,共2页 Medical Information
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