摘要
1975年3月至1987年12月我院收治了经病理证实的睾丸精原细胞瘤病例109例,Ⅰ期73例,Ⅱ期28例,Ⅲ期5例,Ⅳ期3例。治疗方法均为术后加放疗,中晚期的13例会并N-甲酰溶肉瘤素化疗,预后与分期有关。3、5、8年生存率为82.6%、771%、66.7%。主要死因为血道转移.1987年以后对ⅡB期、Ⅲ期于放疗前后采用了以顺铂为主的有计划的联合化疗。结果提示:对于Ⅰ、ⅡA。期患者,单纯隔下放疗即可,ⅡB。、Ⅲ期应放疗合并卡铂为主的联合化疗。
From March 1975 to Dercember 1987, 109 cases with testicular seminoma histopathologically confirmed were treated in Zhejiang Cancer Hospital. Of which,the stage Ⅰ Ⅱ Ⅲ, and Ⅳ were seen in 73 28, 5 and 3 cases respectively. AIl patients were re-ceived operation and radiotherapy. It was also combined with chemotherapy of N-formylisarcolysin in l3 cases with advanced dieases.The prognosis was correlated with stages. The survival rates of 3'5 and 8 years were 82. 6 % 77. 1 % and 66. 7 % respectively. The rnain cause of death was hernatogenous rnetastasis. From 1987,the platinebased chemotherapy were adopted in patients with stage ⅡB~Ⅲ It is shown that, the hypophrenic radiotherapy was feasible in patients with stage Ⅰ~ⅡA, but the cis-platinebased chernotherapy were necereary to be combined with radiotherapy in patients with stage ⅡB~Ⅲ