系统性红斑狼疮患者感染输血传播病毒的检测

Detection of Infection of Transfusion-transmitted Virus in Patients with Systemic Lupus Erythematosus

目的调查系统性红斑狼疮患者感染输血传播病毒的情况和危险因素。方法采用套式聚合酶链反应法检测了71例新入院的系统性红斑狼疮患者血清输血传播病毒(TTV)DNA。结果系统性红斑狼疮患者TTV感染率为31.0%,明显高于对照组。TTV感染与糖皮质激素的用量、免疫抑制剂的使用有关。结论TTV感染是系统性红斑狼疮的常见并发症,系统性红斑狼疮患者继发TTV感染易发因素是大剂量糖皮质激素、免疫抑制剂。

ObJective 1o study tile inlechon oi translusion - transmitted virus（ TTV ） in patients with systemic lupus erythematosus（ SLE ） and to investigate the risk factors of infection. Methods The serum collected form 71 cases with SLE was examined by nest polymerse chain reaction for detecting TFV. Results Incidence of infection of TFV in patients with SLE was 31. 0% ,which was much higher than that of control group. The infection of TTV in patients with SLE was related to many factors,such as dosage of corticosteroids and imnmuosnppressor. Conclusion The infection of TTV has a high morbidity in SLE patients. The risk factors related to infection of TTV are dosage of corticosteroids and immunosuppressor.