摘要
经多因素分析证实耐火尘是鞍钢工人食道癌的危险因素,在均衡了其他因素的作用后,其仍有单独作用,且存在剂量-反应关系.耐火尘在组成和外表形态上的特点是否与其致癌能力有关尚待进一步研究.还发现室内煤烟污染与食道癌发生有关,吸烟与耐火尘暴露,饮酒和室内煤烟污染有协同致癌作用,饮酒和食物中缺乏动物蛋白是食道癌的危险因素,食新鲜水果和蔬菜具有保护作用.
A SPMR study in a large iron-steel company showed that exophageal cancer was significant excess in workers exposed to nilicon dust(SPMR=278,95% CI=165,439).In this light,a case-control study with 125 exophageal cancer cases and 250 controls was intitated.By a multivariate unconditional logistic regression analysis,silicon dust exposure,years of exposure to silicon dust.domestic coal burning fume and alcohol drinking had significant effect on risk, fruit and meat intake had a prostective effect. There are interactions between silicon exposure and eigarette smoking and between domestic coal burning fume and alcohol drinking.
关键词
粉尘
室内煤烟
食道癌
Dust
Esophageal Cancer
Domestic coal