摘要
An improved procedure for the asymmetric synthesis of α-aminoalkylphosphonic acids using S-2-anilinomethylpyrrolidine as the chiral auxiliary was described. The chemical transformations involved in this protocol could proceed under mild reaction condition to provide good chemical and enantiomeric yields.
An improved procedure for the asymmetric synthesis of α-aminoalkylphosphonic acids using S-2-anilinomethylpyrrolidine as the chiral auxiliary was described. The chemical transformations involved in this protocol could proceed under mild reaction condition to provide good chemical and enantiomeric yields.
基金
Project supported by the National Natural Science Foundation of China （Nos. 20272075 and 20072052）.
