运动与下丘脑-垂体-性腺轴(之二:运动对下丘脑-垂体-性腺轴的影响) 被引量：6

Exercise and Hypothalamus-Pituitary-Gonad(HPG) Axis

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摘要有关运动性疲劳产生的的机理及对它如何进行有效预防和消除的研究,一直是令运动医学工作者瞩目的前沿课题。运动性疲劳时出现的机体变化较为复杂,涉及物质代谢、神经、内分泌、免疫等各个方面。其中,神经递质、HPG轴与机体的物质代谢、运动能力及运动后的恢复密切相关。为此,从睾酮的生理作用和调节、神经递质、细胞因子和睾丸间质细胞的调控、反馈调节和运动对下丘脑-垂体-性腺轴的影响等层面,较系统地探讨运动与下丘脑-垂体-性腺轴之间的关系,为加快机体恢复,提高运动能力,以及科学训练提供理论依据。 The studies of the mechanism of sports fatigue and the effective prevention and elimination from exercise fatigue have been a prospective question for the researchers in sports medicine. The physical changes are complicated when exercise fatigue appears, which deals with some aspects of material metabolism, nerves, endocrine, immunization and so on. In particular, neurotransmitter, hypothalamus-pituitary-gonad （HPG） axis have a close relation with body material metabolism and exercise capacity as well as body recovery after exercise. The paper reviews testosterone function and its regulation, nervous transmitters, cytokine and testicle cell feedback regulation as well as effects of exercise on hypothalamus-pituitary -gonad （HPG） axis.Thus, the author systematically investigated the effects of exercise on hypothalamus, pituitary, gonad regulation. The further purpose is to accelerate body recovery and improve exercise capacity and to provide some theoretical proofs for scientific training.

作者常波

机构地区沈阳体育学院运动人体科学系

出处《沈阳体育学院学报》 2005年第6期4-7,共4页 Journal of Shenyang Sport University

基金辽宁省教育厅高等学校科学研究项目项目编号为202253281

关键词运动下丘脑-垂体-性腺轴反馈调节神经内分泌免疫 exercise hypothalamus-pituitary-gonad （HPG） axis feedback regulation nerves endocrine immunization

分类号 G804.7 [文化科学—运动人体科学]

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1Kalra PS, Fuentes M, Sahu A, et al. Endogenous opioid peptides mediate the interleukin-1-induced inhibition of the release of luteinizing hormone ( LH)-releasing hormone and LH [ J ]. Endocrinology. 1990,127(5) :2381-2386.
2Pierroz DD, Catzeflis C, Aebi AC. Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor Ⅰ secretion in intact adult male rats [ J ]. Endocrinology, 1996, 137 ( 1 ):3-12.
3Tuomisto J, Mannisto P. Neurotransmitter regulation of anterior pituitary hormones[J]. Pharmacol Rev, 1985(37) :249-310.
4Brann DW, Mahesh VB. Excitatory amino acids: function and significance in reproduction and neuroendocrine regulation[J]. Front Neuroendocrinol, 1994, 15 ( 1 ): 3-49.
5Brann DW, Mahesh VB. Excitatory amino acids: evidence for a role in the control of reproduction and anterior pituitary hormone secretion[J ]. Endocrine Rev, 1997(18): 678-680.
6Schobitz B. Gene expression and function interleukin-6 and tumor necrosis factor in the brain [J ]. Prog Neurobiol, 1994:397.
7Kalra PS, Fuentes M, Sahu A, et al. Endogenous opioid peptides mediate the interleukin-1-induced inhibition of the release of luteinizing hormone ( LH )-releasing hormone and LH [ J ]. Endocrinology. 1990,127(5) :2381-2386.
8Karanth S, McCann SM. Anterior pituitary hormone control by interleukin 2[J ]. Proc Natl Acad Sci USA, 1991, 88(7):2961-2965.
9Ying SY, Becker A, Ling N, et al. Inhibin and beta type transforming growth factor (TGF beta) have opposite modulating effects on the follicle stimulating hormone (FSH)-induced aromatase activity of cultured rat granulosa cells[J]. Biochem Biophys Res Commun,1986, 136(3) :969-975.
10Arakane F, Kallen CB, Watari H, et al. The mechanism of action of steroidogenic acute regulatory protein (StAR). StAR acts on the outside of mitochondria to stimulate steroidogenesis [J ]. J Biol Chem, 1998, 273(26): 16339-16345.

二级参考文献31

1胡扬,宋东方,佟启良,袁作生,陈洪范.径赛运动员不同训练量课后唾液睾酮的变化及恢复[J].北京体育大学学报,1994,17(1):57-61. 被引量：6
2谢敏豪,方子龙,贺春晓,邓静,高峡,杨则宜,杨天乐.激素分泌的评价方法探讨[J].中国运动医学杂志,1995,14(1):33-35. 被引量：9
3方子龙,谢敏豪,王杉,贺春晓,郑静,杨则宜,杨天乐.运动员血清中黄体生成素生物活性与免疫活性的研究[J].中国运动医学杂志,1996,15(1):18-22. 被引量：9
4马伯龙,龙彦,王晓丽,王维岳,赵敬杰,郝忠东.唾液睾酮碘标放射免疫测定方法的分析[J].实用医学杂志,1996,12(6):356-357. 被引量：3
5[1]Tabata, Y. Atomi, H. Kanehisa, et al. Effect of high-intensity endurance training on isokinetic muscle power[J]. Eur. J. Appl. Physiol Occup. Physiol, 1990, 60: 254.
6[2]Tabata, Y. Atomi, Y. Mutoh, and M. Miyashita. Effect of physical training on the responses of serum adrenocorticotropic hormone during prolonged exhausting exercise[J]. Eur. J. Appl. Physiol Occup.Physiol, 1990, 61:188.
7[3]D. Cumming. Influence of aerobic versus anaerobic exercise on male reproductive hormones[J]. Clin. J. Sport Med, 1996(6): 141.
8[4]Galbo H. The hormonal response to exercise[J]. Diabetes Metab Rev, 1986(1):385-408.
9[5]Christensen NJ, Galbo H. Sympathetic nervous activity during exercise[J]. Annu Rev Physiol, 1983, 45:139-53.
10[6]Vervoorn C, Quist AM, Vermulst LJ, Erich WB, de Vries WR, Thijssen JH. The behaviour of the plasma free testosterone/cortisol ratio during a season of elite rowing training[J]. Int J Sports Med, 1991,(12):257-63.