隐性乳腺癌20例诊治分析

The analysis of diagnosis and treatment for 20 cases of occult breast cancer

目的:探讨隐性乳腺癌的诊断和治疗方法。方珐:对20例隐性乳腺癌患者的临床资料进行回顾性分析。同侧乳腺根治性切除术10例,改良根治术7例,术后辅助化疗15例,术后加放疗5例,3例未手术的给予化疗加免疫治疗。结果:17例乳腺切除标本中见可疑肿物14例,最大直径1.0 cm。术后随访12例,3例2年后死于肺转移,1例5年后死于其他疾病,8例随访6年仍存活。结论:乳头溢液和乳腺局限性腺体增厚对隐性乳腺癌的诊断有重要价值,活检有助于确诊;乳腺癌根治术或改良根治术后应辅以放、化疗。

Objective： To investigate the diagnosis of occult breast cancer （OBC） and its management. Methods： To review and analyze 20 cases with OBC, including 19 female and 1 male case, between 27 to 58 year old with average age 43 years old and course of illness from 2 weeks to 1 year. Among them there were 16 cases with first symptom axillary lymphadenectasis and 4 with supra clavicular lymphadenectasis. They had all been proved to be metastatic adenocarcinoma after lymphadenectomy pathological examination. No obvious lumps were found after clinical examination of both sides of breast among these cases. Results： Same side radical mastectomy was performed on 10 cases. Extended radical mastectomy was performed on 7 cases. Post operation chemotherapy for 15 cases. Post operation radiotherapy for 5 cases. Chemotherapy and immunization therapy were given to the 3 cases which no operation was performed. Conclusions： Nipple discharge and regional mammary gland accumulation have important value to the diagnosis of occult breast cancer diagnosis, Biopsy is helpful to the final diagnoses Radical mastectomy or extended radical mastectomy should be given and followed by radiotherapy and chemotherapy.