微生物细胞表面呈现技术研究进展

The Microbe Cell-surface Engineering Study Progress

微生物细胞表面工程是近年来发展起来的,它利用细胞表面展示技术使外源蛋白固定化 于细胞表面,从而生产微生物细胞表面蛋白。微生物细胞表面工程可用于细胞催化剂、细胞吸附 剂、活疫苗、生物传感器的开发等。微生物细胞表面工程具有广阔的应用前景,但是国内对这一 领域的研究刚起步。在介绍细胞表面工程的基础上,对微生物细胞表面工程技术进展进行了综 述,展望了对该技术的发展。

Microbe cell-surface engineering, which use the microbe cell surface display technology to display foreign proteins on the microbe cell surface to produce cell-surface proteins, was developed in recent years. I t can be utilized to develop cell-catalyst, cell-adsorbent, live vaccine, biosensor and so on, and have a wide application perspective. But in our county, the microbe cell-surface engineering is studied just now. This review explain the development of the microbe cell surface engineering, overview the study and progress of microbe cell-surface engineering, and look this technology into the future.