正常鼓膜表皮树突状细胞的研究

A study of dendritic cell in the epidermis of normal human tympanic membrane

应用抗ＨＬＡ－ＤＲ单克隆抗体，对６例死于各种疾病患者的正常鼓膜表皮进行免疫组织化学观察。结果示：正常鼓膜表皮内有树突状细胞（ＤＣ）分布。提示胆脂瘤基质内之朗罕细胞可能为鼓膜表皮内ＤＣ移入所致。

Langerhans cells(LC ) of the epidermis were identified as members of DC. However,there is no report in the literature concerning the localization of DC in the normal humantympanic membrane. This study was designed to clarify this question,The epidermis from six patients who died from other causes but no history of previous middle ear disease were obtained between lh to 21 h after death. The monoclonal antibody against HLA-DR was used to detect DC. A network of DC was demonstrated in the epidermis of normal human tympanic membrane.