软组织损伤并创面感染病原菌调查

Pathogenic Bacterium Investigation of Soft Tissue Injury Combined with Raw Surface Infection

目的了解骨科软组织损伤并创面感染中细菌分布与耐药菌现状,为临床医生合理使用抗菌药物提供依据.方法采取前瞻性监测及回顾性调查的方法,对我院2001～2004年诊断软组织损伤感染患者病历资料进行总结.结果228例软组织损伤并创面感染患者中,细菌学监测的有154例,其中57例为医院感染;监测标本中104株为阳性,G+球菌66株,G-杆菌34株.结论患者刚入院时,细菌以革兰阳性菌为主,随着患者住院天数的延长,细菌的种类也发生变化,在医院感染病例中细菌的分布是以革兰阴性菌为主;应加强抗菌药物使用和监控,根据药敏结果合理选用抗菌药物.

OBJECTIVE To understand the situation of bacteria distribution and drug-resistant bacteria of soft tissue injury combined with raw surface infection and apply the evidence of rational use of antibacterial to doctor. METHODS The data of the patients diagnosed as soft tissue injury and infection from 2001 to 2004 in our hospital were reviewed retrospectively and monitored prospectively. RESULTS Of 228 patients, 154 cases executed bacteria monitoring, 57 of which suffered hospital infection. Totally 104 samples were bacteria positive, 66 strains being G^＋ cocci and 34 strains G^- bacilli. CONCLUSIONS When patients are just in hospital, the bacteria are mainly G^＋ cocci, and as the time of hospitalization lengthening, the bacteria are varied. The bacteria in patients with hospital infection are mainly G^- cocci; we should enforce the monitoring of antibiotic usage and choose the proper antibiotic on the basis of result of drug sensitivity.