益气养阴汤治疗病毒性心肌炎的疗效及其对IL-2、PFP的影响鄢

Therapeutic effect of supplementing qi and nourishing yin soup treat viral myocarditis,and the effect of IL-2 and PFP

目的探讨益气养阴汤治疗病毒性心肌炎的作用机制。方法收集60例病毒性心肌炎病例,随机分为对照组和治疗组,疗程3、4周,治疗前后检测心肌酶学(CK、CK-MB),心脏超声(EF、LVM、LVMI、SO、CO和CI),血清IL-2及淋巴细胞穿孔素表达水平(PFP)及疗效评价。结果应用益气养阴汤治疗病毒性心肌炎EF上升、LVM下降、LVMI下降有统计学意义(P<0.05);血清IL-2下降、外周血淋巴细胞穿孔素表达水平下降有统计学意义(P<0.05)。结论益气养阴汤治疗病毒性心肌炎有效,免疫作用机制可能与降低外周血IL-2、淋巴细胞穿孔素表达有关。

[Objective] Initial research the mechanisms of supplementing qi and nourishing yin soup treat viral myoearditis, [Methods] 60 viral myoearditis eases were eoUeeted, random divided into control groups and treat group, Course of treatment were 3～4 weeks, every patient examine CK CK-MB EF LVM SO CO CI IL-2 PFP and evaluate therapeutic effect after and before treatment. [Results] Supplementing qi and nourishing yin soup treat viral myoearditis had statistical significance with EF upgrade, with LVM subside and with LVMI subside （P 〈0.05）, The subside of IL-2 and PFP had statistical significance （P 〈0.05）. [Conclusion] Supplementing qi and nourishing yin soup treat viral myoearditis was utility. Immunffaetion mechanism may relate with the subside of IL-2 concentration and PFP express level.