干部体检中脂肪肝的患病情况及相关因数分析

Analysis of the status of fatty liver and related factors in health examination of ocadre

目的分析干部群体中脂肪肝的患病情况,探讨其发病的相关因素。方法对参加健康体检的534名机关干部,做血脂、血糖及血尿酸等生化检查,同时做腹部B超、心电图和胸片等检查,并将检查资料录入微机,对脂肪肝组和非脂肪肝组进行对比分析。结果脂肪肝的检出率为23.6%,男性明显高于女性,约是女性的2.5倍(P<0.01);脂肪肝检出率青年、中年和老年组间无统计学差异(P>0.05);脂肪肝组的体重指数(BMI)、血甘油三酯(TG)、血高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FBG)、餐后2h血糖(PBG2h)和血尿酸(UA)水平与非脂肪肝组比较差异有显著性(P<0.01);脂肪肝组中并存肥胖症、血脂异常、高血压、糖耐量低减、糖尿病和高尿酸血症的发生率显著高于非脂肪肝组(P<0.01)。结论脂肪肝的发病与性别密切相关,肥胖、糖尿病、以高TG血症和低HDL-C血症为主的血脂异常是其发病的重要因素;控制体重、纠正血脂异常和降低糖尿病患者的血糖是防治脂肪肝的重要措施。

[Objective] To analyse the status of fatty liver and to explore the related factors of fatty liver in cadres. [Methods] 534 cases of officials who came to take part in the healthy examination, received measurement of the level of blood lipids, glucose and uric acid, at the same time, to inspect type B ultrasonic waves examination of liver and kidney after measuring electrocardiogram （ECG）, chest-X-ray. The populations with fatty liver were compared with those without fatty liver. [Results] The ratio of fatty liver among the officials is about 23.6%, the male＇s ratio is higher than the female＇s, it＇s about 2.5 times of the female＇s（P 〈0.01）. There was no significant difference in incidence of fatty liver among the young groups, middle ages＇ and the old groups（P 〉0.05）; but there was significant difference between the fatty liver and the non-fatty liver groups of their body mass index （BMI）, the lever of blood triglyceride （TG）, high density lipoprotein-cholesterol （HDL-C）, fasting blood glucose （FBG）, 2-hour postprandial blood glucose （PBG2h） and uric acid（UA）（P 〈0.01 ）; The ratios of obesity, dyslipidemia, hypertension, impaired glucose tolerance （IGT）, diabetes mellitus （DM）, hyperuricemia in fatty liver group were significantly higher than non-fatty liver group （P 〈0.01）. [Conclusions] Fatty liver is associated with sex. Obesity, DM, dyslipidemia which is especial for hypertriglyceridemia and low HDL-C are important factors of fatty liver; To control the body weigh, redress the abnormality of blood lipid, reduce the BG of the DM are the most important measures to prevent and cure the fatty liver.