阻塞性睡眠呼吸暂停综合征多导睡眠图分析及短期疗效观察

PSG analysis and short-term curative effect observation of OSAS

目的探讨阻塞性睡眠呼吸暂停综合征的多导睡眠图特征并观察双水平正压通气治疗OSAS的短期疗效。方法经多导睡眠图检查确诊OSAS患者46例,对照组(单纯鼾症组)12例,分析比较两组睡眠参数。对34例中重度OSAS患者进行睡眠时BiPAP辅助通气并比较治疗前后PSG参数变化。结果与对照组相比,OSAS患者夜间睡眠结构紊乱,主要为深睡眠减少、浅睡眠相对增加、快速动眼相(REM)睡眠减少、睡眠潜伏期缩短、呼吸暂停或低通气次数增加、夜间平均及最低动脉血氧饱和度下降(P<0.05)。34例中重度OSAS患者经BiPAP辅助通气后,临床症状显著改善,AHI、夜间平均及最低动脉血氧饱和度、最长呼吸暂停时间较治疗前有显著改善(P<0.05)。结论OSAS患者存在睡眠结构紊乱,BiPAP可改善患者的临床症状及睡眠结构,是治疗OSAS的有效手段。

[Objective] To analyze the characteristics of the polysomnography （PSG） of OSAS and observe the short-term curative effect of BiPAP on OSAS. [Methods] There were 46 OSAS patients diagnosed through PSG and 12 primary snore patients as a control group, and the sleep parameters of the two groups were analyzed and compared. BiPAP assisted ventilation was used on 34 moderated and serious patients when they were sleeping. The PSG parameters before and after the treatment were compared. [Results] Compared with the control group, OSAS patients had sleep disorders, which were manifested as less NREM Ⅲ ＋Ⅳ, NREM Ⅰ ＋ Ⅱ, less REM sleep, shortened sleep latency, more sleep apnea or hypopnea and decrease of nighttime average and minimum artery saturation oxygen （P 〈0.05）. Since treated with BiPAP assisted ventilation, the clinical symptoms of the 34 moderate and serious patients were improved obviously, AHI, nighttime average and minimum artery saturation oxygen （P 〈0.05）, the maximum apnea period also had obvious improvement. [Conclusion] OSAS patients have sleep disorders, BiPAP can improve the patients＇ clinical symptoms and sleep structure, it is an effective method to treat OSAS.