基础医学研究进展的还原论与系统论

Reductionism and System Theory in the Development of Medical Science

从分子生物学、基因组学、蛋白质组学到糖组学,以还原论为哲学指导的医学研究已经取得了辉煌成果,与此同时,以系统论为哲学指导的系统生物学也日益受到关注,更被誉为新世纪生物学、医学研究的核心驱动力。还原论是系统论的基础和条件,而系统论则是还原论的归宿和终点,整个基础医学的研究进展经历了一场由还原论到系统论、再实现还原论与系统论辩证统一的演化过程。医学科学的发展历程闪耀着人类哲学理性思考的光辉,同时哲学思维也对医学研究进展做出了巨大的指导作用。

From molecular biology,genomics, proteomics to glycomics, the medical research guided by the reductionism has achieved great brilliances,at the same time the system biology,crowned as kernel driving forces for the biomedieal research in the new contrary, which takes the system theory as its philosophy guide, are drawing more and more attention from the community of science. The reductionism is the bases and prerequisites for the system theory, while the system theory is the end point and termination for the reductionism. The history of the basic medical re.search reflects an evolution processing from the reductionism to the system theory, then to the unity of the two theories. The development of medical sciences in full of the glare of philosophy; the philosophy almakes great contribution to guide the Progress of biomedical research.