丹东地区犬恶丝虫病的血清流行病学调查

Serological Survey of Canine Dirofilariasis in Dandong

本调查首次应用犬恶丝虫同种纯化抗原进行ELISA检测对辽宁省丹东地区12个品种,1048条不同年龄、不同饲养条件的犬进行犬恶丝虫的血清流行病学调查,同时与虫检法进行比较。结果表明:丹东地区犬恶丝虫的血清阳性率为28.5%,虫检的阳性率为22.6%。虫检法阳性犬的检测结果与ELISA法一致,且ELISA法的检出率高于虫检法。此外,调查结果还表明:犬恶丝虫的感染率与犬的品种、性别无关;与犬的饲养条件及年龄有关。ELISA法在丹东地区犬恶丝虫病的血清流行病学调查中的应用,有效地提高了该病的检出率,为该地区对犬恶丝虫病的早期预防和治疗提供了有力依据。

Serological survey of canine Dirofilariasis was conducted by ELISA with purified Dirofilaria immitis antigen in 1048 dogs of 12 breeds that in different ages and different breeding condition in Dandong. The results showed that： serum positive rate was 28.5% ,and that of the worm examination was 22.6%. The positive rate detected by ELISA was higher than by worm examination, and the coincidence rate with the clinical examination was 100%. The infectious rate had no relation to the breeds and sex, but it related to the breeding condition and age. It provided powerful evidence for the prevention and treatment of canine Dirofilariasis. An application of the developed indirect ELISA had a great meaning to Dirofilariasis and it is important to prevent this disease.