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罗哌卡因与布比卡因在经皮肾穿刺取石术的效果比较

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摘要 目的比较中低浓度罗哌卡因与布比卡因在经皮肾穿刺取石术的临床效果.方法选择经皮肾穿刺取石术病人80例,随机均分为两组,即罗哌卡因组(RP组)和布比卡因组(BP组);两组均于T10~11行硬膜外腔穿刺并头侧置管,成功后RP组应用0.375%罗哌卡因,BP组应用0.375%布比卡因行硬膜外阻滞.测定两组感觉与运动阻滞的起效时间、持续时间、运动阻滞的程度,比较两组患者的VAS评分、不良反应及术后病人活动能力的恢复情况.结果两组患者感觉和运动阻滞的起效时间与持续时间相似(P>0.05);运动阻滞的程度BP组较RP组稍强,但组间比较差异无显著性(P>0.05);两组病人的VAS评分差异无显著性(P>0.05);呼吸抑制发生率BP组(20%)明显高于RP组(5%),组间比较差异有显著性(P<0.05);术后活动能力RP组较BP组恢复快,组间比较差异有显著性(P<0.05).结论罗哌卡因和布比卡因均可应用于经皮肾穿刺取石术,具有相似的麻醉质量,但中低浓度的罗哌卡因术中呼吸抑制发生率低、术后活动能力恢复快,相对于等浓度的布比卡因更有利于术中对病人的管理及术后病人的恢复.
出处 《南华大学学报(医学版)》 2005年第4期560-562,共3页 Journal of Nanhua University(Medical Edition)
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