川芎嗪与硝酸甘油治疗急性左心功能不全疗效比较

Treatment of acute left heart dysfunction with“chuanxiongqin”and nitroglycerin:comparison of therapeutic effectiveness

比较川芎嗪与硝酸甘油治疗急性左心功能不全的疗效和异同。用川芎嗪治疗急性左心功能不全３０例，同时与３０例硝酸甘油治疗组进行疗效比较。结果：川芎嗪组与硝酸甘油组治疗后血压、心率均有明显降低（Ｐ均＜０．００１），但两组间无显著性差异；显效率川芎嗪为３６．６７％，硝酸甘油组为１０．００％，两组比较有极显著性差异（Ｐ＜０．００１）；总有效率川芎嗪组为９３．３０％，硝酸甘油组为８６．６７％，两组比较无显著性差异；对谷草转氨酶的恢复川芎嗪组不如硝酸甘油组。作者认为：川芎嗪对各种病因引起的急性左心功能不全均有效，且未发现明显副作用。

To investigate the therapeutic effectiveness of “chuanxiongqin”,30 patients with acute left heart dysfunction were treated with “chuanxiongqin”and 30 with nitroglycerin as the controls.The blood pressure and heart rate were markedly decreased in both groups( P <0 001 in both groups),but there was no significant difference in the decreases between the two groups.The significantly effective rate was 36 67% in “chuanxiongqin”group and 10 00% in nitroglycerin group with a very significant difference between the two groups( P <0 01).The overall effective rate was 93 30% in “chuanxiongqin”group and 86 67% in nitroglycerin group without significant difference between the two groups.The recovery of glutamic oxaloacetic transaminase was less satisfactory in “chuanxiongqin”group than nitraglycerin group.It is considered that “chuanxiongqin”is effective in the treatment of acute left heart dysfunction of different etiologies.No obvious side effects were found in using “chuanxiongqin”.